Methylenglycerinsalicylicacidester and process of making same.



UNITED STATES PATENT OFFICE.

KARL STEPHAN AND TADDAUS EMILEWICZ, OF BERLIN, GERMANY, ASSIGNORS TO CHEMISCHE FABRIK AUF AGTIEN, (VORM. E. SCHERING,)

OF BERLIN, GERMANY.

METHYLENGLYCERINSALICYLICACIDESTER AND PROCESS OF MAKING SAME.

Specification of Letters Patent.

. Patented Oct. 10, 1905.

Application filed April 24, 1905- Serial No. 257,209.

To all whom, it may concern:

is esterified with salicylic acid, a new compound is produced which may be called methylenglycerinsalicylicacidester and which answers the formula This new compound can be produced as follows: Three kilograms of salicylic acid are dissolved by the aid of heat in ten kilograms of the above-mentioned combination of glycerin and formaldehyde, which may be obtained by one of the processes of Schulz and Tollens.

.(See Liebz'gs Ammlen, Vol. 289, page 29.)

tion of the ether the product of the reaction is purified by distillation in a vacuum.

This new compound is an oily liquid having the specific gravity of 1.344 at 15 centigrade. It boils at 200 centigrade at a pressure of twelve millimeters with slight decomposition, is easily soluble in ether, alcohol, benzene, chloroform, castor-oil, more diflicultly soluble in olive and sesame oils, insoluble in water, petroleum ether, glycerin, and Vaseline. The compound is split up by diluted acids or alkalies into salicylic acid, glycerin, and formaldehyde.

The new compound may be used as a local remedy for rheumatism.

We claim as our invention 1. The herein-described new compound, the constitution of which answers the formula said compound being an oily liquid of the specific gravity of 1.34 at 15 centigrade, easily soluble in ether, alcohol, benzene, chloroform, castor-oil, more diflicultly soluble in olive and sesame oils, insoluble in water, petroleum ether, glycerin and Vaseline, and splitting up by diluted acids or alkalies into salicylic acid, glycerin and formaldehyde, substantially as set forth.

2. The process of producing the herein-described new compound, which consists in reacting upon a combination of glycerin and formaldehyde with salicylic acid, and separating the product of the reaction, substantially as set forth. I

In testimony whereof we have signed our names to this specification in the presence of two subscribing witnesses.

KARL STEPHAN. TADDAUS EMILEWICZ. Witnesses:

HENRY HASPER, WOLDEMAR HAUPT. 

